Thyroid Status in Relation to Age and Gender - A Cross Sectional Study

Amrut A Dambal; Samata Padaki; Anita Herur; Sangappa V Kashinakunti; R Manjula; K Gurupadappa

doi:10.4103/2321-7006.301936

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ORIGINAL ARTICLE

Year : 2013 \| Volume : 1 \| Issue : 2 \| Page : 37-40

Thyroid Status in Relation to Age and Gender - A Cross Sectional Study Amrut A Dambal¹, Samata Padaki², Anita Herur³, Sangappa V Kashinakunti⁴, R Manjula⁵, K Gurupadappa⁶ ¹ Assistant Professor, Dept of Biochemistry, MRIMS, Hyderabad, AP, India ² Assistant Professor, Dept of Physiology, MRIMS, Hyderabad, AP, India ³ Associate Professor, Dept of Physiology, SNMC, Bagalkot, Karnataka, India ⁴ Associate Professor, Dept of Biochemistry, SNMC, Bagalkot, Karnataka, India ⁵ Assistant Professor, Dept of Community Medicine, SNMC, Bagalkot, Karnataka, India ⁶ Professor and Head, Dept of Biochemistry, SIMS, Shimoga, Karnataka, India Correspondence Address: Samata Padaki Assistant Professor, Dept of Physiology, MRIMS, Hyderabad, AP India Source of Support: None, Conflict of Interest: None DOI: 10.4103/2321-7006.301936

Background: Thyroid disorders have become much more common in the present days and so are its resultant complications or sequelae. There are marked variations in thyroid function with age and sex, evident in all of the in vitro hormone and protein measurements. Objective: To correlate the thyroid status with age and gender. Methods: 500 subjects of all age group and both genders from the general population of Bagalkot, Karnataka were included in the study. Subjects suffering from thyroid disorders were excluded. Non-Fasting venous samples were collected from all the subjects, serum T3, T4, and TSH levels were estimated by microplate immunoenzymometric assay. Statistical analysis was done by ANOVA and unpaired ‘t’ test. Results: It was observed that T3 and T4 levels declined but TSH levels raised, as the age advanced. T3 and T4 levels were lower and TSH levels higher in female subjects as compared to male subjects, in the age group of 21 – 40 years. Conclusion: The variability in the thyroid status has to be borne in mind during evaluation and treatment of thyroid disorders.



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Age variation; Gender variation; Tri-iodo-thyronine (T3); Tetra-iodo-thyronine (T4); Thyroid stimulating hormone (TSH)

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