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Year : 2016  |  Volume : 4  |  Issue : 2  |  Page : 114-117

Clinical behaviour of ocular surface squamous neoplasia (OSSN) in HIV positive patients

1 Assistant professor of Ophthalmology, Sarojini Devi Eye Hospital, Osmania Medical College, Hyderabad, India
2 Professor I/C of Ophthalmology, Gandhi Medical College, Hyderabad, India
3 Assistant Professor of Pathology, Osmania Medical College, Hyderabad, India

Correspondence Address:
P Padmavathi
Assistant professor of Ophthalmology, Sarojini Devi Eye Hospital, Osmania Medical College, Hyderabad
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2321-7006.302248

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Background: A lot of Ocular Surface Squamous Neoplasia(OSSN) may go unnoticed as they are asymptomatic and usually slow-growing. The prevalence of OSSN is more in tropical region and varies from 12 cases /million/ year in Uganda to 0.3 cases / million/ year in United States of America, possibly related to sunlight exposure. Objective: To study the clinical behaviour of Ocular Surface squamous neoplasia (OSSN) in HIV positive patients. Methods: This is a retrospective study done at the department of the oculoplastics and orbital diseases, Sarojini Devi Eye Hospital Hyderabad over a period of three years from February 2012 to January 2015. 26 cases of HIV positive patients with OSSN were included in the study and non HIV cases were excluded. Results: In our study of 26 cases 17 were males and 9 were females and average age of presentation was 34 years 10 to 15 years younger than non HIV cases. Histopathologically 18 cases were squamous cell carcinoma, 5 cases were carcinoma in situ and 3 cases were with moderate to severe dysplasia. Recurrence was seen in 8 cases (32.1%). Conclusion: OSSN presents at a younger age in HIV positive patients with aggressive behaviour clinically and histopathologically with more chances of recurrence.

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