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ORIGINAL ARTICLE
Year : 2017  |  Volume : 5  |  Issue : 1  |  Page : 6-9

Role of collagen cross linking in keratoconus


1 Professor & HOD, Department of Ophthalmology, MRMCW, Hyderabad, India
2 Senior Resident, SD Eye Hospital, Hyderabad, India

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2321-7006.302539

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Background: Corneal grafting is associated inherent risks that could result in permanent loss of vision and significantly affect the quality of life. Corneal collagen cross linking is a new technique that can either prevent corneal transplantation or delay the progress of keratoconus. Advanced tools of the day can measure the contours of the cornea perfectly to adopt the new technology of corneal collagen cross linking. Objective: To evaluate the outcome of the collagen cross linkage using riboflavin 0.1% and ultraviolet A radiation of wavelength 370 nm. Methods: This prospective interventional trial of corneal collagen cross-linking was carried out in 50 eyes of 30 patients with progressive keratoconus from January 2013 to July 2014. The paired t test was used to check the significance of the difference between 2 dependent groups. The level of statistical significance was set at P<0.05 Results: 80% of the study subjects in the age group of 16 to 25 years. 60% of the study group was males. 34% of the study group was with severing keratoconus. Based on pachymetry findings, 84% of the study group classified as moderate keratoconus. Conclusion: Visual acuity improved in keratoconus patients by 1.5 lines of Snellen's equivalent, henceforth CXL can be treatment modality for visual improvement along with other techniques.


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